• Take VRAYLAR exactly as your healthcare provider tells you to take it. Do not change the dose or stop taking VRAYLAR without first talking to your healthcare provider. • Take VRAYLAR 1 time each day with or without food. • If you take too much VRAYLAR, call your healthcare provider or Poison Control Center at 1-800-222-1222 orDosage for depressive episodes in bipolar I disorder. If you’re taking Vraylar for depressive episodes of bipolar I disorder, your starting dosage will be 1.5 mg once per day. On day 15 of your ...The recently approved atypical antipsychotic Vraylar (cariprazine) appears to be a safer alternative to Risperdal (risperidone) with a similar risk profile to Abilify (aripiprazole), according to a recent analysis by the health informatics firm Advera Health Analytics Inc. gwolters/Shutterstock. “This is something that we typically do when ...VRAYLAR is not approved for the treatment of patients with dementia-related psychosis. ... for whom alternative, effective, but potentially less harmful treatments are not available or appropriate. In patients who do require chronic treatment, use the lowest dose and the shortest duration of treatment producing a satisfactory clinical response ...VRAYLAR ® (cariprazine) List Price. The list price, also known as the wholesale acquisition cost (WAC), for a 30-day supply of VRAYLAR is $1,446.55 as of January 2024. However, the amount you will pay will largely depend on your health insurance coverage. Call 1-800-678-1605 to find out how much VRAYLAR will cost for you.Alcohol and Vraylar have many common side effects because they are both central nervous system depressants. Alcohol can cause a worsening of symptoms and side effects of bipolar disorder or schizophrenia. You are at an increased risk of some of the following side effects when you combine the two: Low blood pressure.As the reaction to Nvidia (NVDA) shows, the S&P 500 is becoming more like the S&P 10, writes stock trader Bob Byrne, who says Nvidia and a handful of other giant te...Oct 3, 2019 ... SAN DIEGO — Alternatives with new mechanisms ... SAN DIEGO — Alternatives with new mechanisms of ... Vraylar (cariprazine, Allergan);. #1 ...Vraylar has an average rating of 5.8 out of 10 from a total of 472 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect. Wellbutrin has an average rating of 6.8 out of 10 from a total of 748 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 23% reported a negative effect. Vraylar 3 mg capsule. Color: white,blue-green Shape: oblong Imprint: FL 3 . This medicine is a white purple, oblong, capsule imprinted with "FL" and "6". Look up another drug . Serious - Use Alternative (41) alfentanil. cariprazine and alfentanil both increase sedation. Avoid or Use Alternate Drug. Limit use to patients for whom alternative treatment options are inadequate. amobarbital. amobarbital will decrease the level or effect of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.VRAYLAR: If a strong CYP3A4 inhibitor is initiated, reduce the current dosage of VRAYLAR by half. For patients taking 4.5 mg daily, the dosage should be reduced to 1.5 mg or 3 mg daily. For patients taking 1.5 mg daily, the dosing regimen should be adjusted to every other day. When the CYP3A4 inhibitor isAdvertisement As it usually goes in any branch of show business, success and fame only happens to a slim minority of those who seek out stardom. That goes for drag queens to a grea...We would like to show you a description here but the site won’t allow us.Olanzapine has an average rating of 5.8 out of 10 from a total of 1059 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 33% reported a negative effect. Vraylar has an average rating of 5.8 out of 10 from a total of 472 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative … Vraylar 3 mg capsule. Color: white,blue-green Shape: oblong Imprint: FL 3 . This medicine is a white purple, oblong, capsule imprinted with "FL" and "6". Look up another drug . Vraylar (cariprazine) and Zyprexa (olanzapine) are atypical antipsychotics indicated for the treatment of schizophrenia bipolar disorder.. Side effects of Vraylar and Zyprexa that are similar include sleepiness/drowsiness, restlessness, weight gain, headache, stomach/abdominal pain, constipation, pain in the extremities, dry mouth, back pain, and …The identified doses were then used to calculate equivalence ratios. For example, if the minimum effective dose of olanzapine was 7.5 mg/d and that of asenapine was 10 mg/d, the asenapine dose that is equivalent to 1 mg/d olanzapine would be 10/7.5 = 1.33 mg/d. We made several modifications ( supplementary webappendix 1 presents … Eligible patients whose insurer does not cover VRAYLAR ® (cariprazine) or where coverage restrictions have not been satisfied may pay as little as $75 per 30-day supply for each of up to twelve (12) prescription fills. Check with your pharmacist for your copay discounts. Maximum savings limit applies; patient out-of-pocket expenses may vary. More about Vraylar ( cariprazine ) Ratings & Reviews. Buspirone has an average rating of 5.9 out of 10 from a total of 1334 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 36% reported a negative effect. Vraylar has an average rating of 5.8 out of 10 from a total of 474 ratings on Drugs.com. 46% of reviewers reported a ...Seroquel has an average rating of 7.0 out of 10 from a total of 677 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 21% reported a negative effect. Vraylar has an average rating of 5.8 out of 10 from a total of 474 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect.Compare Rexulti alternatives | Abilify | Risperdal | Vraylar | Zyprexa | Seroquel | Natural alternatives | How to switch meds. Rexulti, Otsuka America Pharmaceutical’s brand-name for the prescription antipsychotic medication brexpiprazole, has been approved by the U.S. Food and Drug Administration (FDA) as an adjunct to be used along with an antidepressant medicine to treat major depressive ...The price of 30 tablets of Vraylar (1.5 mg) averages around $1200, which works out to approximately $40/day. The price for 30 tablets of Rexulti (1 mg) is about $1100, working out to roughly $36/day. Therefore, if you are in the higher dosage range for Vraylar (i.e., 6 mg/day), then Rexulti could be less expensive on a per-day treatment basis.How to say VRAYLAR in English? Pronunciation of VRAYLAR with 3 audio pronunciations, 1 meaning, 7 translations and more for VRAYLAR.Dosage for depressive episodes in bipolar I disorder. If you’re taking Vraylar for depressive episodes of bipolar I disorder, your starting dosage will be 1.5 mg once per day. On day 15 of your ...VRAYLAR is not approved for the treatment of patients with dementia-related psychosis. ... Each hard gelatin capsule contains a white to off-white powder of cariprazine HCl, which is equivalent to 1.5, 3, 4.5, or 6 mg of cariprazine base. In addition, capsules include the following inactive ingredients: gelatin, magnesium stearate ...The most common side effects include difficulty moving or slow movements, tremors, uncontrolled body movements, restlessness and feeling like you need to move around, sleepiness, nausea, vomiting, indigestion, constipation, feeling tired, trouble sleeping, increased appetite, and dizziness. These are not all the possible side effects of VRAYLAR.Restlessness. Treatment with Vraylar may cause restlessness. This can include akathisia, which is a sense of restlessness and uncontrollable urges to move your legs. Restlessness and akathisia are among the most common side effects reported in Vraylar’s clinical studies.Vraylar (cariprazine) takes time to work and patients often see a gradual reduction in symptoms over several weeks.Symptoms tend to continue to improve the longer the medication is taken. Some symptoms may not completely resolve however. Vraylar is an atypical antipsychotic used in the treatment of schizophrenia, the acute …1. Vraylar is approved to treat more health conditions than Latuda. Both Vraylar and Latuda are antipsychotic medications. They’re part of a group of …Is it just egotism or is there a hidden benefit to talking about yourself in the third person (like Donald Trump)? HowStuffWorks investigates. Advertisement In pop-culture parlance...Vraylar · Vuity™ · Vumerity® · Vusion · Vyepti™ · Vyndaqel ... Community Alternative Care Waiver. The Community ... For more information, view th...VANCOUVER, British Columbia, June 03, 2021 (GLOBE NEWSWIRE) -- Sonoro Gold Corp. (TSXV: SGO | OTCQB: SMOFF | FRA: 23SP), (“Sonoro” or the “Compa... VANCOUVER, British Columbia, J...Vraylar: La cariprazine appartient au groupe de médicaments appelés agents antipsychotiques. Elle s'utilise pour soigner la schizophrénie et le trouble bipolaire. Elle ne constitue pas un traitement curatif de ces troubles médicaux, mais elle aide à prendre en charge leurs symptômes en modifiant les actions de certains messagers chimiques dans …We would like to show you a description here but the site won’t allow us.VRAYLAR is approved in adults to treat bipolar I depression and for the short-term treatment of manic or mixed episodes that happen with bipolar I disorder. While anyone can develop bipolar I disorder, it often starts in the late teen or early adult years and lasts a lifetime. ∥ Inclusive of all indications.Vraylar 3 mg capsule. Color: white,blue-green Shape: oblong Imprint: FL 3 . This medicine is a white purple, oblong, capsule imprinted with "FL" and "6". Look up another drug .Vraylar (cariprazine) is an atypical antipsychotic used to treat schizophrenia and bipolar I disorder in adults. It can also be used as an add-on medication to help with major depressive disorder (MDD). Vraylar (cariprazine) is taken by mouth once a day. Some common side effects of this medication include uncontrolled muscle movements, …More about Vraylar ( cariprazine ) Ratings & Reviews. Venlafaxine has an average rating of 6.4 out of 10 from a total of 2753 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 28% reported a negative effect. Vraylar has an average rating of 5.8 out of 10 from a total of 474 ratings on Drugs.com. 46% of reviewers reported ...AbbVie has filed with the FDA to extend the uses of its bipolar disorder therapy Vraylar to include adjunctive therapy for major depressive disorder, part of a plan to build sales of the drug to ... use alternative during and x10 days after isocarboxazid use: combo may incr. risk of CNS depression, psychomotor impairment, hypotension, incl. orthostasis, syncope (additive effects) ivosidenib Vraylar (cariprazine) Serious - Use Alternative (41) alfentanil. cariprazine and alfentanil both increase sedation. Avoid or Use Alternate Drug. Limit use to patients for whom alternative treatment …VRAYLAR ® (cariprazine) List Price. The list price, also known as the wholesale acquisition cost (WAC), for a 30-day supply of VRAYLAR is $1,446.55 as of January 2024. However, the amount you will pay will …In the past 30 days, VRAYLAR has had 2,256 airings and earned an airing rank of #483 with a spend ranking of #385 as compared to all other advertisers. Competition for VRAYLAR includes REXULTI (Depression), TRINTELLIX, Latuda, ABILIFY, NUPLAZID and the other brands in the Pharmaceutical & Medical: Rx: Depression, Bipolar & Insomnia …Abilify Alternatives Compared. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Abilify Vraylar Lamictal. ... Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar disorder. Vraylar is usually well-tolerated and less likely than some other ...have lower-cost alternatives in. Tiers 1 and 2. Ask your doctor if switching ... VRAYLAR ORAL. CAPSULE. 2. PA; QL (31 per 31 days). VRAYLAR ORAL. CAPSULE,DOSE.The ones that treat bipolar depression are cariprazine (Vraylar), lurasidone (Latuda), olanzapine-fluoxetine combo (Symbyax), and quetiapine (Seroquel). Among them, lurasidone offers a good balance of efficacy and tolerability. Lurasidone’s main problems â nausea, akathisia, cost, and lack of evidence in mania â are less likely to occur ...That’s why Vraylar in America is nearly $1,500.00 for a one-month supply, while in Canada the same amount of medication is available for around $300.00. Until Vraylar is available as a generic medication, which may not be for several years, it’s a good idea to look at Vraylar alternatives or consider ways to save on this medication.Vraylar is an oral antipsychotic drug for schizophrenia and bipolar I disorder. It has a boxed warning for increased risk of suicidal thoughts or behaviors in certain …VRAYLAR is not approved for treating patients with dementia-related psychosis. VRAYLAR and antidepressants may increase suicidal thoughts or actions in some children and young adults especially within the first few months of treatment or when the dose is changed. Depression and other mental illnesses are the most important causes of suicidal ...Aug 1, 2019 ... The drug information provided is intended for reference only and should not be used as a substitute for medical advice. If you have specific ... The most common side effects include difficulty moving or slow movements, tremors, uncontrolled body movements, restlessness and feeling like you need to move around, sleepiness, nausea, vomiting, indigestion, constipation, feeling tired, trouble sleeping, increased appetite, and dizziness. These are not all the possible side effects of VRAYLAR. The Food and Drug Administration (FDA) has approved Vraylar ® (cariprazine) as adjunctive therapy to antidepressants for the treatment of major depressive disorder (MDD) in adults. The approval ...Cariprazine (Vraylar), Bipolar Disorder and Schizophrenia, Pill. Esketamine (Spravato), Treatment-Resistant Depression, Nasal Spray. Paliperidone PalmitateThere's been a dramatic change to the hurricane models, and Hurricane Dorian is now expected to become a major hurricane. Here's the impact on travel. Update: Some offers mentioned...VRAYLAR ® (cariprazine) is an adjunctive or add-on treatment for major depressive disorder. Eligible commercially insured patients may pay as little as*: $0 for VRAYLAR: both 30- and 90-day fills. $0 for a generic antidepressant. Get your savings card and talk to your doctor about a 90-day prescription to save more time and money at the pharmacy.Schizophrenia: The incidences within the recommended dose range (VRAYLAR 1.5–3 mg/day and 4.5–6 mg/day vs placebo) were EPS (15%, 19% vs 8%) and akathisia (9%, 13% vs 4%). US-VRA-220402. Please also see full Prescribing Information, including Boxed Warnings. See key VRAYLAR pharmacokinetics data. See Important Safety Information …Eligible patients whose insurer does not cover VRAYLAR (cariprazine) or where coverage restrictions have not been satisfied may pay as little as $75 per 30-day supply for each of up to twelve (12) prescription fills. When insurance covers VRAYLAR (cariprazine), eligible patients may pay as little as $15 for each of up to four (4) 90-day ...Alcohol and Vraylar have many common side effects because they are both central nervous system depressants. Alcohol can cause a worsening of symptoms and side effects of bipolar disorder or schizophrenia. You are at an increased risk of some of the following side effects when you combine the two: Low blood pressure.Vraylar is a prescription drug used to treat bipolar I disorder, depression, and schizophrenia. ... However, this article should not be used as a substitute for the knowledge and expertise of a ...VRAYLAR may cause serious side effects, including: Stroke (cerebrovascular problems) in elderly people with dementia-related psychosis that can lead to death Neuroleptic malignant syndrome (NMS): Call your healthcare provider or go to the nearest hospital emergency room right away if you have high fever, stiff muscles, confusion, increased ...Vraylar, with the generic name cariprazine, is an atypical antipsychotic medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of Bipolar Depression. It is available in capsule form and works by targeting specific receptors in the brain, including dopamine D2 and D3 receptors, as well as serotonin 5-HT1A …More about Vraylar ( cariprazine ) Ratings & Reviews. Abilify has an average rating of 6.0 out of 10 from a total of 1173 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 34% reported a negative effect. Vraylar has an average rating of 5.8 out of 10 from a total of 474 ratings on Drugs.com. 46% of reviewers reported a ...Advertisement As it usually goes in any branch of show business, success and fame only happens to a slim minority of those who seek out stardom. That goes for drag queens to a grea...To register for an educational event over the phone, please call 1-888-335-8430. VRAYLAR (cariprazine) is indicated in adults as adjunctive therapy to antidepressants for the treatment of major depressive disorder (MDD), for the treatment of depressive episodes associated with bipolar I disorder (bipolar depression), for the acute treatment of ...VRAYLAR is not approved for treating patients with dementia-related psychosis. VRAYLAR and antidepressants may increase suicidal thoughts or actions in some children and young adults especially within the first few months of treatment or when the dose is changed. Depression and other mental illnesses are the most important causes of suicidal ...VRAYLAR may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills which may lead to falls that can cause fractures or other injuries. Seizures (convulsions) may occur with VRAYLAR and other antipsychotic drugs.Apple is cracking down on Twitter's content moderation shortcomings. Removal from the App Store would be costly. As the owner of Twitter, Elon Musk cannot afford to pick a fight wi...*Depending on your insurance coverage, eligible patients may pay as little as $5 per 30-day supply for each of up to twelve (12) prescription fills or as little as $5 for each of up to four (4) 90-day prescriptions if VRAYLAR ® (cariprazine) if covered without coverage restrictions (eg, prior authorization, step therapy, or otherwise), and for those who are taking VRAYLAR ® (cariprazine) as ...Vraylar (cariprazine) may be taken either in the morning or at night, depending on your preference.. Cariprazine, the active ingredient of Vraylar, and its metabolites have a long half-life: 2 to 4 days for cariprazine, 1 to 2 days for one active metabolite called DCAR, and approximately 1 to 3 weeks for another active metabolite …Nov 16, 2016 ... Appendix B: Therapeutic Alternatives. This table provides a listing of preferred alternative therapy recommended in the approval criteria ...Malaysia is the latest country to limit sand exports to Singapore. Singapore needs a lot of sand. As a tiny island-nation acutely aware of its small size, it has long reclaimed lan...Seroquel has an average rating of 7.0 out of 10 from a total of 677 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 21% reported a negative effect. Vraylar has an average rating of 5.8 out of 10 from a total of 474 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect.Allergan. Vraylar Prescribing Information. https://www.vraylar.com. Abilify (aripiprazole) and Vraylar (cariprazine) are antipsychotic medications used to treat schizophrenia and mania. Abilify is also used to treat depression, bipolar disorders, autistic disorder, and some irritable behavior disorders.Oct 4, 2023 · That’s why Vraylar in America is nearly $1,500.00 for a one-month supply, while in Canada the same amount of medication is available for around $300.00. Until Vraylar is available as a generic medication, which may not be for several years, it’s a good idea to look at Vraylar alternatives or consider ways to save on this medication. What is a natural alternative to Vraylar? Our program includes a comprehensive approach to neurotransmitter rehabilitation and neurotoxin removal. We provide tapering under medical oversight to ensure a safe and effective process. Additionally, we focus on correcting the diet and incorporating orthomolecular medicine … Eligible patients whose insurer does not cover VRAYLAR (cariprazine) or where coverage restrictions have not been satisfied may pay as little as $75 per 30-day supply for each of up to twelve (12) prescription fills. When insurance covers VRAYLAR (cariprazine), eligible patients may pay as little as $15 for each of up to four (4) 90-day ... Cariprazine is marketed as VRAYLAR ® in the U.S., and in addition to being approved as an adjunctive therapy to antidepressants for the treatment of MDD in adults, it is FDA-approved to treat ...Vraylar alternatives might be a better choice for improvements in mental wellness. Vraylar is a relatively new antipsychotic drug, that has been approved for treating schizophrenia, and as an add-on medication in treating episodic bipolar mania and depression.1. it may be a good time to consider alternatives to Vraylar that may be less risky ...Cariprazine is marketed as VRAYLAR ® in the U.S., and in addition to being approved as an adjunctive therapy to antidepressants for the treatment of MDD in adults, it is FDA-approved to treat ...Vraylar is a medication that belongs to a class of drugs called atypical antipsychotics. It contains the active ingredient cariprazine, which works by modulating certain neurotransmitter receptors in the brain, including dopamine and serotonin. By targeting these neurotransmitters, Vraylar helps to restore the balance of chemicals in …The mechanism of action of VRAYLAR is unknown. The efficacy of VRAYLAR is thought to be mediated through a combination of: Central dopamine D 2. Partial agonist. Serotonin 5-HT1A. Partial agonist. Serotonin 5-HT2A. Antagonist. The first and only dopamine and serotonin partial agonist FDA approved for the most.Abilify Alternatives Compared. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Abilify Vraylar Lamictal. ... Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar disorder. Vraylar is usually well-tolerated and less likely than some other ...Seroquel has an average rating of 7.0 out of 10 from a total of 677 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 21% reported a negative effect. Vraylar has an average rating of 5.8 out of 10 from a total of 474 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 36% reported a negative effect.VRAYLAR is approved in adults to treat bipolar I depression and for the short-term treatment of manic or mixed episodes that happen with bipolar I disorder. While anyone can develop bipolar I disorder, it often starts in the late teen or early adult years and lasts a lifetime. ∥ Inclusive of all indications.
Apr 9, 2024 · Other drugs are available that can treat your condition. Some may be a better fit for you than others. If you’re interested in finding an alternative to Vraylar, talk with your doctor. . Northern animal hospital phoenix az
More about Vraylar ( cariprazine ) Ratings & Reviews. Bupropion has an average rating of 7.0 out of 10 from a total of 2857 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. Vraylar has an average rating of 5.8 out of 10 from a total of 474 ratings on Drugs.com. 46% of reviewers reported a ...Compare Rexulti alternatives | Abilify | Risperdal | Vraylar | Zyprexa | Seroquel | Natural alternatives | How to switch meds. Rexulti, Otsuka America Pharmaceutical’s brand-name for the prescription antipsychotic medication brexpiprazole, has been approved by the U.S. Food and Drug Administration (FDA) as an adjunct to be used along with an antidepressant medicine to treat major depressive ... VRAYLAR ® (cariprazine) is an adjunctive or add-on treatment for major depressive disorder. Eligible commercially insured patients may pay as little as*: $0 for VRAYLAR: both 30- and 90-day fills. $0 for a generic antidepressant. Get your savings card and talk to your doctor about a 90-day prescription to save more time and money at the pharmacy. Podcasts are no substitute for treatment but they can provide helpful tools to manage anxiety. Here are the 9 best anxiety podcasts for 2022. Does anxiety make your home, social, o...DENVER, July 13, 2021 /PRNewswire/ -- National direct primary care provider Everside Health ('Everside'), formerly Paladina Health, Activate Healt... DENVER, July 13, 2021 /PRNewsw...Cholinergic rebound, where the second drug has less cholinergic activity. Symptoms may be severe but relatively brief and predictable- nausea, vomiting, restlessness, anxiety, …Vraylar is an oral antipsychotic drug for schizophrenia and bipolar I disorder. It has a boxed warning for increased risk of suicidal thoughts or behaviors in certain … VRAYLAR (cariprazine) is indicated in adults as adjunctive therapy to antidepressants for the treatment of major depressive disorder (MDD), for the treatment of depressive episodes associated with bipolar I disorder (bipolar depression), for the acute treatment of manic or mixed episodes associated with bipolar I disorder, and for the treatment ... Vraylar Alternatives Compared. Vraylar (cariprazine) Lamictal (lamotrigine) Lamotrigine. Prescription only. Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... more. Prescription only.Vraylar package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. ... Each hard gelatin capsule contains a white to off-white powder of cariprazine HCl, which is equivalent to 1.5, 3, 4.5, or 6 mg of cariprazine base. In addition, capsules include the following ...The ones that treat bipolar depression are cariprazine (Vraylar), lurasidone (Latuda), olanzapine-fluoxetine combo (Symbyax), and quetiapine (Seroquel). Among …VRAYLAR is not approved for treating patients with dementia-related psychosis. VRAYLAR and antidepressants may increase suicidal thoughts or actions in some children and young adults especially within the first few months of treatment or when the dose is changed. Depression and other mental illnesses are the most important causes of suicidal ...it's been amazing. I've been on vraylar for 3 months now at 3mg and it's totally controlling my bipolar 1. also no weight gain, I'm actually losing weight for once! 5. Reply. halfdayallday123. • 1 mo. ago. Pretty good. My heart rate went up a little but not to unsafe levels. Seems to blunt the bad emotions pretty good..
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